Learn More About Mixed Anxiety and Depressive Disorder

It is conceivable to experience both depression and anxiety simultaneously: According to a global poll conducted in 2015, 41.6% of respondents said they experienced both serious depression and an anxiety condition over a 12-month period. Keep reading to understand more about these two conditions combined.


It can be hard to deal with both depression and anxiety simultaneously. Along with the pain that these feelings cause, you also have to deal with the difficult situations that made them happen in the first place.

It’s normal to feel sad or worried when bad things happen; these feelings are a normal part of life. But there are times when sadness and fear are too much to handle. These feelings could get very strong, last longer than we thought they would, or come on suddenly, leaving us unsure of where they came from. The information here about anxiety and depression might help you if you feel like your sadness and stress are affecting your health and making it hard for you to enjoy life.

What is Mixed Anxiety and Depressive Disorder?

People who have Mixed Anxiety and Depressive Disorder, or MADD, can find it very hard to deal with things. The disorder is a complicated mix of anxiety and depression symptoms, and people who have it often feel like their emotions are going all over the place. It can be challenging to fight between intense worry and deep sadness.

While it’s normal to feel anxious and sad sometimes, MADD is different because these feelings last for a long time and get in the way of your daily life and health. There is help and understanding out there for people who are dealing with MADD. Don’t forget that you’re not alone in this and can get help to heal and get better.

What is Anxiety Disorder?

The National Institute on Mental Health says that having periods of worry is a normal part of life. You might feel anxious when you have a problem at work, before a test, or before making a very important choice. Anxiety illnesses, on the other hand, are more than just occasional fear or dread.

The main difference between anxiety and depression is that anxiety doesn’t go away and can get worse over time, so it’s important to get help for anxiety as soon as possible. The signs could make it hard to do normal things like work, school, or connect with others. Anxiety disorders come in many forms, such as generalized anxiety disorder, panic disorder, and several disorders linked to phobias.

What is Depression?

The National Institute of Mental Health says that depression, which is also called Major Depressive Illness or Clinical Depression, is a relatively common but severe mood condition. It causes severe symptoms that make it hard to do everyday things like sleep, eat, and work. Before someone can be diagnosed with sadness, they must show signs of it for at least two weeks.

Depression needs to be treated when the symptoms last for a long time and don’t go away. This is because different types of depression are a little different and can show up in strange scenarios.

What Are The Symptoms of Mixed Anxiety & Depressive Disorder?

Physical SymptomsPsychological Symptoms
FatigueConstant worry
HeadachesPersistent sadness
Muscle tensionIrritability
Rapid heartbeatDifficulty concentrating
NauseaFear of the future
Digestive issuesFeelings of hopelessness
RestlessnessLow self-esteem
InsomniaLoss of interest in activities
SweatingGuilt or self-blame
Shortness of breathThoughts of self-harm
DizzinessAnxiety about physical health
Trembling or shiveringPervasive negative thoughts
PalpitationsSocial withdrawal
FidgetingDifficulty making decisions
If you notice any of these signs, they could mean that you are depressed or anxious. It’s important to remember that only a skilled mental health professional can accurately diagnose depression or anxiety after a complete evaluation that takes into account your specific needs and situation. Remember that you can talk to your primary care provider about your worries about your mental health at any time. You can also look at our private online test below to get the help and support you need. Help is out there for you if you need it for your mental health.
The primary sign of Mixed Anxiety and Depressive Disorder is often a persistent low, depressed, or hopeless mood. In contrast, the significant symbol of anxiety is an abundance of worry, uneasiness, and fear.
The primary sign of Mixed Anxiety and Depressive Disorder is often a persistent low, depressed, or hopeless mood. In contrast, the significant symbol of anxiety is an abundance of worry, uneasiness, and fear.

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Generalized anxiety disorder and depression can both have emotional and physical symptoms.
Mixed anxiety depressive disorder can both have emotional and physical symptoms.

What Causes Mixed Anxiety Depressive Disorder?

The exact causes of Mixed Anxiety and Depressive Disorder (MADD) are not fully understood, as mental health conditions often result from a complex interplay of factors. However, several vital factors may contribute to the development of MADD:

  1. Biological Factors: Imbalances in brain chemistry and the functioning of neurotransmitters can play a role in MADD. Genetic factors may also increase susceptibility to this condition.
  2. Psychological Factors: Stressful life events, trauma, or ongoing stress can contribute to the development of MADD. Coping with difficult situations may lead to both anxiety and depressive symptoms.
  3. Personality Traits: Certain personality traits, such as perfectionism or a tendency to ruminate on negative thoughts, may increase the risk of MADD.
  4. Environmental Factors: A lack of social support, financial difficulties, or challenges in personal relationships can contribute to the onset of MADD.
  5. Physical Health: Some physical health conditions or chronic illnesses may exacerbate symptoms of MADD.
  6. Substance Abuse: Substance abuse, including alcohol and drug use, can both lead to and result from MADD.

What’s the Difference Between Anxiety and Depression?

AspectAnxietyDepression
Primary EmotionExcessive worry, fear, or uneaseOverwhelming sadness, hopelessness
Focus of ConcernFuture-oriented, often about potential threats or uncertaintiesPast or present, often focused on perceived losses or failures
Physical SymptomsRestlessness, muscle tension, rapid heartbeat, shortness of breath, sweatingFatigue, low energy, changes in sleep patterns, changes in appetite and weight
Cognitive SymptomsExcessive worrying, racing thoughts, difficulty concentratingPervasive sadness, feelings of worthlessness, difficulty making decisions
Emotional ResponseFear, apprehension, unease, irritabilityPersistent sadness, loss of interest or pleasure, emotional numbness
Behavioral SymptomsAvoidance, fidgeting, seeking reassurance, repetitive behaviorsSocial withdrawal, decreased activity, neglect of responsibilities
DurationOften episodic, symptoms related to specific stressors or situationsLonger-lasting, typically lasting for weeks or months
TriggersOften triggered by perceived threats, stress, or specific phobiasMay be triggered by life events, but can also occur without apparent cause
Treatment ApproachCognitive-behavioral therapy (CBT), exposure therapy, relaxation techniquesCognitive-behavioral therapy (CBT), psychotherapy, medication (antidepressants)
PrevalenceCommon, affecting millions of people worldwideCommon, with a significant global impact
Some people have symptoms of both anxiety and depression. To get an accurate diagnosis and the proper treatment, it’s crucial to get a complete evaluation by a mental health expert.

Shared Symptoms of Mixed Anxiety and Depressive Disorder

You should know that people who have depression, anxiety, or both may not have the same symptoms. However, the symptoms of these two disorders often overlap. Mixed Anxiety and Depressive Disorder (MADD) is characterized by several symptoms that are often seen together:

  • Alterations in Sleep Patterns: Both anxiety and sadness can make it hard to fall asleep or stay asleep, or they can cause changes in the way you sleep.
  • Levels of Energy: People with MADD may have times when they are nervous or agitated (anxiety) and times when they are tired and have little energy (depression).
  • Increased Irritability: People with MADD may become more irritable or easily upset, often responding strongly to small things that set them off.
  • Problems with Memory, Focus, and Concentration: Cognitive functions can be harmed, making it hard to remember things, focus, concentrate, and make choices.
  • Unexplained Physical Symptoms: People with MADD may have aches, pains, or stomach problems that don’t seem to have a clear medical cause.
  • Rumination: People with both anxiety and depression can experience rumination, which is a loop of negative, dark, or sad thoughts that they find hard to stop or control.
  • Anxiety-Related Rumination: Thinking about bad things that might happen all the time or worrying too much, even when you can’t change your worries.
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MADD vs. Adjustment Disorder With Mixed Anxiety and Depressed Mood

“Adjustment disorder mixed anxiety and depression” is not the same thing as “Mixed Anxiety and Depressive Disorder.” There are some changes between these diagnostic groups:

Mixed Anxiety and Depressive Disorder (MADD): MADD, which is also called “cyclothymia,” is a diagnostic category for people who have both anxiety and depressive symptoms but don’t fully meet the standards for either an anxiety or depressive disorder. These signs may happen simultaneously, and the person may feel restless, anxious, sad, and lose interest in doing things.

Adjustment Disorder with Mixed Anxiety and Depressed Mood: This condition is more specific and is considered an adjustment disorder. It happens after a particular event or source of stress in life and includes both anxious and sad feelings. The main thing to note is that the symptoms are linked to a specific stressor, and they generally get better within six months of getting rid of it.

To sum up, MADD is a broader term for people who have both mixed anxiety and depressive symptoms but not the specific time-limited and stressor-related traits of Adjustment Disorder with Mixed Anxiety and Depressed Mood. A trained mental health worker is the only one who can make the correct diagnosis after carefully looking at a person’s symptoms and their situation.

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Different Types of Adjustment Disorder Mixed Anxiety and Depression

The DSM-5 lists six types of adjustment disorders:

  • Adjustment disorder with depressed mood: Symptoms include feelings of sadness, hopelessness, crying, and lack of joy from previous pleasurable things.
  • Adjustment disorder with anxiety: Symptoms include feeling worried, anxious, and overwhelmed. You also have trouble concentrating. Separation anxiety is a dominant symptom in children.
  • Adjustment disorder with mixed anxiety and depressed mood: Symptoms include feeling both anxious and depressed.
  • Adjustment disorder with disturbance of conduct: Symptoms include behavioral issues such as acting rebellious, destructive, reckless, or impulsive.
  • Adjustment disorder with mixed disturbance of emotions and conduct: Symptoms include anxiety, depression, and behavioral issues.
  • Adjustment disorder unspecified: Symptoms include physical symptoms such as headaches, body aches, stomach aches, heart palpitations, or insomnia.
If you experience sadness for more than two weeks, speak with your doctor. If you are contemplating suicide, call emergency services to get immediate medical attention.
If you experience sadness for over two weeks, speak with your doctor. If you are contemplating suicide, call emergency services to get immediate medical attention.

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Adjustment Disorder With Mixed Anxiety And Depressed Mood Treatment Plan

It might occasionally be more challenging to treat co-occurring depression and anxiety than one disorder on its own. Even if you receive treatment for one ailment, several symptoms may continue or interact.

For instance:

  • You can’t stop thinking about how many things are going wrong in your life or how they might worsen. Your energy and motivation to keep trying eventually become depleted by these anxieties, leaving you feeling depressed and hopeless.
  • You are unable to interact with people the way you would like to because of social anxiety. You want to meet new people, yet you usually avoid social situations. You are left feeling alone, depressed, and guilty as a result, especially when you consider the squandered possibilities, yet you are powerless to change anything.

A mental health care provider might suggest combining different treatment modalities because what reduces anxiety and depression symptoms may not always reduce depression symptoms and vice versa.

Potential remedies for depression and anxiety include:

Mixed Anxiety-Depressive Disorder Therapy

Therapy comes in a variety of forms and can be used to treat depression or anxiety.

For instance, interpersonal therapy for depression teaches you how to communicate effectively to express yourself and meet your emotional needs. Phobias are a sort of anxiety that can be treated using exposure therapy, a method that helps you become more at ease in dreaded situations.

Other methods are available to address both conditions:

  • Cognitive behavioral therapy (CBT) teaches techniques to identify, challenge, and reframe unwanted thoughts and behavior patterns.
  • Mindfulness-based cognitive therapy teaches mindfulness techniques along with behavioral techniques to help you begin to manage unwanted feelings and stay present through them instead of becoming overwhelmed.
  • Acceptance and commitment therapy teaches strategies to accept unwanted or distressing thoughts, stay present, and commit to positive activities that fulfill your personal values.
  • Problem-solving therapy. This approach teaches using coping skills to manage mental health symptoms and life experiences that cause stress and other emotional turmoil.

Mixed Anxiety and Depressive Disorder Medications

Additionally, psychotropic drugs can lessen the signs and symptoms of anxiety and depression. But because it doesn’t help you deal with the root of those symptoms, your physician or psychiatrist will typically advise therapy in addition to medication.

A therapist, such as a psychiatrist, might suggest:

  • Antidepressants include selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). In some cases, these medications may also relieve anxiety symptoms.
  • Anti-anxiety medications: including benzodiazepines, buspirone (Buspar), and beta-blockers. These medications can ease anxiety symptoms but may not improve depression symptoms. Benzodiazepines also carry a high risk of dependence, so your prescriber may try other medications first.
  • Mood stabilizers: These medications may help treat depression symptoms that don’t respond to antidepressants alone.

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The precise definition of “dual diagnosis,” also known as co-occurring disorders, can vary among institutions. In general, it refers to the concurrent treatment of an individual who has received diagnoses of both a substance use disorder and a mental health disorder.

Addressing dual-diagnosis clients constitutes a crucial element of our inpatient treatment program because co-occurring disorders are strongly associated with instances of substance abuse. Crafting a comprehensive treatment plan that encompasses the physical aspects of withdrawal, the psychological ties to substance use, and the management of underlying mental health conditions is fundamental to setting clients on the path to success.

A thorough mental health evaluation uncovers treatment possibilities. Collaborating with mental health counselors and medical professionals grants access to behavioral therapy and medication-based interventions.

At our dual diagnosis treatment center, We Level Up is committed to delivering top-tier care. We understand the intricate interplay of mental and substance abuse disorders and how they can perpetuate a cycle of addiction. We provide specialized dual-diagnosis treatment to offer clients the best prospects for genuine recovery and long-lasting well-being.

Acknowledging that you may be living with a mental illness can be challenging. Nevertheless, once it is accurately diagnosed and treated, addressing the co-occurring substance abuse issue becomes considerably more manageable. Only qualified medical professionals can diagnose these underlying conditions. Suppose you suspect that you are grappling with a co-occurring disorder alongside addiction. In that case, we strongly encourage you to seek a reputable treatment center to commence your journey to recovery. Contact We Level Up today.

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  5. Merck Manual, Consumer Version. Adjustment Disorders (https://www.merckmanuals.com/home/mental-health-disorders/anxiety-and-stress-related-disorders/adjustment-disorders). Last reviewed 8/2023. Mixed Anxiety and Depressive Disorder Related articles
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