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How to Microdose Mushrooms and Does It Help Anxiety and Depression?

A recent study reveals that regular usage of tiny doses of the hallucinogen psilocybin can enhance mental health and help treat some of the symptoms of anxiety and depression. Keep reading to learn about microdosing mushrooms.

Difference Between Anxiety and Depression – How to Microdose Mushrooms?

Anxiety and depression difference: The fact that one term denotes a single sickness while the other denotes a collection of ailments is a significant distinction between anxiety and depression.

In reality, depression is one illness. There are numerous distinct symptoms (see below). And different people may experience it very differently. However, the term “depression” only refers to one illness.

The word “anxiety” can indicate a number of different things. We all experience anxiety occasionally, and the word “anxiety” can be used to describe that feeling simply. However, when we use the word anxiety in a medical context, it actually refers to anxiety disorder.

Some less frequent conditions are included under anxiety. These include panic disorders and phobias. However, generalized anxiety disorder is the most prevalent (GAD). In the US, a generalized anxiety disorder may affect four to five out of every 100 persons. In this post, we’ll concentrate on generalized anxiety.

What is Anxiety Disorder?

According to The National Institute on Mental Health, periodic anxiety is a standard component of life. When faced with a challenge at work, before a test, or before making a crucial decision, you could experience anxiety. However, anxiety disorders involve more than just passing apprehension or terror.

Anxiety and depression difference: It’s critical to get anxiety treatment as soon as you can since, for someone with an anxiety condition, the anxiety does not go away and can actually worsen over time. The symptoms might affect daily tasks like work performance, academic progress, and interpersonal connections. Generalized anxiety disorder, panic disorder, and various phobia-related disorders are only a few of the several types of anxiety disorders.

Anxiety and depression difference: People with a generalized Anxiety disorder (GAD) display excessive Anxiety or worry, most days for at least 6 months, about many things such as personal health, work, social interactions, and everyday routine life circumstances. Fear and Anxiety can cause significant problems in areas of their life, such as social interactions, school, and work. 

What is Depression?

Depression (also known as Major Depressive Illness or Clinical Depression) is a common but significant mood disorder, according to the National Institute of Mental Health. It produces severe symptoms that interfere with your ability to function on a daily basis, including sleeping, eating, and working. The signs of depression must last for at least two weeks before a diagnosis may be made.

Depression treatment is required when depressive symptoms are chronic and do not go away since some types of depression are slightly different or may arise in unusual situations.

Types of Depression

  • Persistent depressive disorder (also called dysthymia): is a depressed mood that lasts for at least two years. A person diagnosed with persistent depressive disorder may have episodes of major Depression along with periods of less severe symptoms, but symptoms must last for two years to be considered a persistent depressive disorder.
  • Psychotic Depression: occurs when a person has severe depression plus some form of psychosis, such as having disturbing false fixed beliefs (delusions) or hearing or seeing upsetting things that others cannot hear or see (hallucinations). The psychotic symptoms typically have a depressive “theme,” such as delusions of guilt, poverty, or illness.
Depression (also known as Major Depressive Illness or Clinical Depression) is a common but significant mood disorder.
Depression (also known as Major Depressive Illness or Clinical Depression) is a common but significant mood disorder.
  • Bipolar disorder: is different from Depression, but it is included in this list because someone with bipolar disorder experiences episodes of extremely low moods that meet the criteria for major Depression (called “Bipolar Depression”). But a person with bipolar disorder also experiences extreme high – euphoric or irritable – moods called “mania” or a less severe form called “hypomania.”
  • Postpartum Depression: is much more serious than the “baby blues” (relatively mild depressive and anxiety symptoms that typically clear within two weeks after delivery) that many women experience after giving birth. Women with postpartum Depression experience full-blown major Depression during pregnancy or after delivery (postpartum depression). The feelings of extreme sadness, anxiety, and exhaustion that accompany postpartum depression may make it difficult for these new mothers to complete daily care activities for themselves and/or their babies.
  • Seasonal affective disorder: is characterized by the onset of Depression during the winter months, when there is less natural sunlight. This Depression generally lifts during spring and summer. Winter Depression, typically accompanied by social withdrawal, increased sleep, and weight gain, predictably returns every year in seasonal affective disorder.
  • SAD Seasonal Depression (Depressed SAD): A form of depression known as seasonal affective disorder (SAD) is triggered by the changing of the seasons; it starts and ends about at the same periods each year. If you have SAD like the majority of people do, your symptoms begin in the fall and last through the winter, draining your energy and making you cranky. Typically, these symptoms go away in the spring and summer. SAD less frequently results in depression in the spring or early summer and clears up in the fall or winter.
    SAD treatment options include medications, psychotherapy, and light therapy (phototherapy).

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Depression Fact Sheet

Depression Overview

Depression is a group of illnesses like depression or bipolar disorder that are connected to mood elevation or depression


Types of Depression

  • Clinical Depression: A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
  • Persistent depressive disorder: A mild but long-term form of depression.
  • Bipolar disorder: A disorder associated with episodes of mood swings ranging from depressive lows to manic highs.
  • Bipolar II disorder:  A type of bipolar disorder characterized by depressive and hypomanic episodes.
  • Postpartum depression: Depression that occurs after childbirth.

Depression Treatments

  • Support group: A place where those pursuing the same disease or objective, such as weight loss or depression, can receive counseling and exchange experiences.
  • Cognitive behavioral therapy: A conversation treatment that aimed to change the negative attitudes, actions, and feelings connected to psychiatric discomfort.
  • Counseling psychology: A subfield of psychology that handles issues with the self that are connected to work, school, family, and social life.
  • Anger management: To reduce destructive emotional outbursts, practice mindfulness, coping skills, and trigger avoidance.
  • Psychoeducation: Mental health education that also helps individuals feel supported, validated, and empowered
  • Family therapy: psychological counseling that improves family communication and conflict resolution.

Depression and Anxiety Statistics

It’s critical to understand the distinction between anxiety and depression. Anxiety, in its most basic form, is an excessive feeling of worry, whereas depression, in its most basic form, is an excessive feeling of worthlessness and hopelessness. It is conceivable for someone to experience depression and anxiety simultaneously.


6.8 million

GAD affects 6.8 million adults or 3.1% of the U.S. population, yet only 43.2% are receiving treatment.

Source: National Institute on Mental Health

19 million

19 million adults experience specific phobias, making it the most common anxiety disorder in America.  

Source: ADAA2020

17.3 million

Major depressive disorder affects approximately 17.3 million American adults or about 7.1% of the U.S. population aged 18 and older.

Source: National Institute of Mental Health


Microdosing Mushrooms: How to Microdose Mushrooms for Anxiety and Depression?

A recent study reveals that regular usage of tiny doses of the hallucinogen psilocybin can enhance mood and mental health.
A recent study reveals that regular usage of tiny doses of the hallucinogen psilocybin can enhance mood and mental health.

A recent study reveals that regular usage of tiny doses of the hallucinogen psilocybin can enhance mood and mental health.

Over the course of a 30-day follow-up, those who microdose mushrooms reported “small- to medium-sized” improvements in their symptoms of stress, anxiety, and depression compared to those who did not.

In this observational study, which was released on June 30 in Nature-Scientific Reports, 180 people served as the control group while over 900 participants reported microdosing psilocybin within the previous month.

According to a news statement from study author Zach Walsh, Ph.D., a psychology professor at the University of British Columbia Okanagan Campus in Kelowna, “This is the largest longitudinal study of this form of microdosing psilocybin to date and one of the few studies to engage a control group.”

He continued, “[The results] contribute to the expanding discussion concerning the therapeutic potential of microdosing.”

Benefits of Microdosing Mushrooms

Microdose Mushrooms: Mental health benefits 

When it comes to psychedelics, microdosing is taking drugs in doses that are insufficient to have an adverse effect on daily life. Depending on the dosage, it could be taken three to five times each week.

According to the 2021 Global Drug Survey (GDS), 1 in 4 psychedelic users reported microdosing on LSD or psilocybin mushrooms within the previous year. The poll also discovered that around one-third of those who used psychedelics microdose another psychedelic substance, despite the fact that these two chemicals are the most frequently used for microdosing.

A challenge for this kind of research, according to Dustin Hines, Ph.D., assistant professor of neuroscience in the department of psychology at the University of Nevada, Las Vegas, is precisely defining the size of that dose. Despite the fact that most people perceive a microdose as being extremely small.

How often to microdose mushrooms? He said that the right microdose may vary from person to person and situation to situation. “When determining a microdose, people are trying to have normal cognitive functioning — they can still carry out their work obligations or other responsibilities without feeling a detrimental influence,” he said.

Participants performed many moods and mental health assessments as part of the new study, reporting their recent use of microdosing psychedelic mushrooms and noting a variety of changes.

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Microdosing Magic Mushrooms: Possible Psychomotor Benefits

Researchers used a smartphone finger-tapping test to measure psychomotor symptoms of neurodegenerative illnesses like Parkinson’s disease and Multiple Sclerosis in addition to examining mental health effects.

This tapping test was used to assess improvements in psychomotor performance in individuals 55 years of age or older who microdose mushrooms. The effects of “stacking,” or mixing psilocybin and a non-psychedelic substance, were also examined by researchers.

The researchers discovered that combining psilocybin with lion’s mane, a non-psychedelic fungus, and niacin, a B vitamin, had no impact on the changes in mood or mental health. However, the psychomotor performance of older people who microdose mushrooms and coupled psilocybin with both of these drugs were more likely to be enhanced.

Mushroom Microdose: Positive Results, But Research is Observational

A portion of participants from a bigger, earlier study by the same researchers, which was published in November 2021 in Nature-Scientific ReportsTrusted Source, were utilized in the new study.

In a previous study, it was discovered that those who microdose either psilocybin (microdose mushrooms) or LSD experienced reduced levels of anxiety, depression, and stress than those who did not.

In addition, a smaller 2019 study discovered that those who used modest amounts of psychedelics experienced fewer depressive and stressful symptoms as well as less distractibility. Non-microdosers were not used in this study as a control group, nevertheless.

It’s also crucial to keep in mind that, although being the largest study of its sort to date, the new one is still observational rather than a randomized controlled trial (RCT). Because of this, it was difficult for researchers to adequately control for variables including age, gender, baseline mental health, and type of treatment that might have an impact on the results.

These kinds of variables might also have an impact on how each person reacts differently to psilocybin.

“Who enters these trials is one factor that varies greatly. Some people can handle depression well but struggle greatly with anxiety, and vice versa, according to Hines. Therefore, a microdose may have a completely different impact on someone with high levels of anxiety compared to someone with high levels of depression.

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Mushroom Microdosing: Results May Vary Based on ‘Expectancy’

The design of the new trial prevented the researchers from controlling for “expectancy,” a phenomenon whereby subjects expect to benefit from psilocybin since they are aware that they are taking it.

This is a frequent issue in research involving psychedelics as well as other studies in which a medication is challenging to conceal from the participants (i.e., studies of acupuncture, ice therapy, and electrostimulation).

The University of Nevada, Las Vegas Rochelle Hines, Ph.D., an assistant professor of neuroscience in the department of psychology, said, “The power of anticipation is immense, and it’s very difficult to control for in these sorts of experiments.” Although anticipation was not even a consideration when designing the study, this does not necessarily imply that the findings are inaccurate.

How much is a microdose of mushrooms? When it comes to psychedelics, microdosing is taking drugs in doses that are insufficient to have an adverse effect on daily life. Depending on the dosage, it could be taken three to five times each week.
How much is a microdose of mushrooms? When it comes to psychedelics, microdosing is taking drugs in doses that are insufficient to have an adverse effect on daily life. Depending on the dosage, it could be taken three to five times each week.

Microdose Mushroom: More Rigorous Research Needed

Due to the fact that psilocybin, LSD, and other psychedelics are now prohibited in the United States by federal law, conducting psychedelic research has historically been difficult.

The Food and Drug Administration (FDA) has recently given psychedelics “breakthrough therapy” status and is currently promoting the scientific study, despite the fact that previous clinical trials on psychedelics have been contested in the past.

And despite the fact that psychedelic medications like psilocybin may have therapeutic value, the negative risks are not fully known, necessitating further thorough investigation.

Long-term usage of psilocybin mushrooms raises the possibility of heart valvulopathy or valve damage. Psilocybin, when consumed, is broken down by the liver into the pharmacological substance psilocin, which binds to serotonin receptors in the heart.

According to Rochelle Hines, these kinds of possible concerns need to be thoroughly examined over an extended period of time in order to fully determine the dangers and advantages of microdosing psilocybin.

“It appears like psilocybin might not offer too much hazard in that aspect for infrequent use,” she said. But I’m not sure that we have a lot of longitudinal data looking at regular chronic users to determine what the possible impact of this substance on the heart is.

Microdosing Mushroom: Stigma Around Psychedelics

Dustin Hines noted that while he is happy with the new study’s methodology and findings, he is also struck by the fact that scientists still need to persuade the public that some psychedelic substances have positive effects. He claimed that although psilocybin and LSD have a low risk of addiction, especially when compared to legal narcotics like tobacco and alcohol, psychedelics nonetheless suffer from a bad reputation.

According to Sherry Walling, Ph.D., a clinical psychologist with a license and the host of the podcast Mind Curious, which examines the advantages of psychedelics for mental health, “they are not particularly unsafe drugs to microdose.” “Overdose and addiction risk profiles are quite low.”

Since psilocybin is thought to have very low toxicity, psilocybin-related deaths are actually quite uncommon. As a result, scientists are looking at psychedelics as potential treatments. Source to Trust for Substance Use Disorders. Walling said, “There’s a really nuanced story here about how substances can be harmful to us, but they can also be extraordinarily healing.

Magic Mushrooms Microdose: How to Microdose Mushrooms for Migraines?

A two-beer buzz is frequently used to describe the felt effects of the tiny doses of psychedelics used to treat cluster headaches. However, they still have a much smaller impact than the results of a recreational dose. Fewer side effects than those associated with their prescribed medications may also be experienced by patients. A dose for clusters may provide the patient with slightly brighter blue skies for a few hours after taking it.

There is no question that psychedelics can treat cluster headaches. However, there is one drawback: in order to get help, patients must break the law. Research into psychedelic remedies for cluster headaches is hindered by regulations because of the legal status of psychedelic drugs. Nevertheless, the Drug Enforcement Agency (DEA) appears to be moving in the opposite direction of legalization, proposing to add five new psychedelic molecules to Schedule I of the Controlled Substances Act on January 14, 2022, despite the evidence that psychedelics may be able to treat cluster headaches and a variety of other untreatable medical conditions.

How to Microdose Mushrooms for Fibromyalgia 

Fibromyalgia’s mystery is being dispelled by new research, which is beginning to suggest that it is an inflammatory autoimmune disorder. Psilocybin for fibromyalgia pain control might be a potent weapon in your management toolbox. Psilocybin is one of the incredibly few medications with the capacity to reduce neuroinflammation, a condition that is exceedingly difficult to treat.

The medical profession has a history of mistreating and demonizing the fibromyalgia population. It is a relief to get concrete evidence that the disease is not just “genuine,” but also obviously visible on testing.

Sadly, recognizing your enemy does not mean the battle is over. Neuroinflammation, the inflammation linked to fibromyalgia, is resistant to our existing autoimmune therapies.

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We Level Up Dual Diagnosis Treatment

The exact definition of dual diagnosis (also referred to as co-occurring disorders) can differ between institutions.  However, it is generally described as the specific treatment of someone who has been diagnosed with a substance use disorder and a mental health disorder at the same time.

Treating dual-diagnosis clients is a critical aspect of our inpatient treatment experience because co-occurring disorders are strongly correlated with instances of substance abuse. Creating a treatment plan that addresses the physical aspects of withdrawal, the psychological connection with drug use, and managing underlying mental health disorders is part of setting clients up for success. 

A thorough mental health analysis identifies possibilities for treatment.  Meeting with mental health counselors and medical care providers means access to behavioral therapy and medication treatment.

At our dual diagnosis treatment center, We Level Up can implement the highest quality of care. We recognize the fragile complexities of how mental and substance abuse disorders can influence others and sometimes result in a vicious cycle of addiction.  That’s why we offer specialized treatment in dual-diagnosis cases to provide the most excellent chance of true healing and long-lasting recovery.

It can be challenging to accept that you may be living with a mental illness, but once it is properly diagnosed and treated, treating the presenting case of substance abuse can be magnitudes easier. Only a properly trained medical professional can diagnose these underlying conditions.  If you believe you are suffering from a disorder alongside addiction, we urge you to seek a qualified treatment center to begin your journey to recovery. Call We Level Up today.

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