Is ADHD Genetic? What You Need to Know

The question “Is ADHD genetic?” has been extensively studied, and the answer is affirmative. Genetic factors contribute significantly to the risk of developing ADHD.


Attention deficit hyperactivity disorder (ADHD or ADD) is a neurological condition with multiple potential causes. The exact origins of ADHD symptoms remain elusive despite several hypotheses within the medical community. Researchers believe a gene linked to dopamine production, a neurotransmitter governing the brain’s ability to sustain consistent attention, might be associated with ADHD. However, comprehensive studies substantiating this link are notably scarce amidst prevalent misconceptions and myths about ADHD today.

Is ADHD Genetic?

Contrary to popular belief, ADHD is not attributable to factors such as inadequate parenting, excessive sugar consumption, or excessive video game use. Instead, it is a biologically rooted disorder stemming from brain-based factors. Various investigations employing brain imaging and other research methods have unveiled notable differences in the brains of individuals diagnosed with ADHD. Additionally, studies indicate that a child diagnosed with ADHD is about four times more likely to have a family member similarly diagnosed with the condition.

Attention deficit hyperactivity disorder (ADHD or ADD) is a neurological condition with multiple potential causes. The exact origins of ADHD symptoms remain elusive despite several hypotheses within the medical community. Researchers believe a gene linked to dopamine production, a neurotransmitter governing the brain’s ability to sustain consistent attention, might be associated with ADHD. However, comprehensive studies substantiating this link are notably scarce amidst prevalent misconceptions and myths about ADHD today.

Contrary to popular belief, ADHD is not attributable to factors such as inadequate parenting, excessive sugar consumption, or excessive video game use. Instead, it is a biologically rooted disorder stemming from brain-based factors. Various investigations employing brain imaging and other research methods have unveiled notable differences in the brains of individuals diagnosed with ADHD. Additionally, studies indicate that a child diagnosed with ADHD is about four times more likely to have a family member similarly diagnosed with the condition.

What Do the Studies Say About ADHD Hereditary?

The possibility of developing ADHD tends to run in families. A recent study involving 2.4 million individuals found that when one parent had ADHD, around 17 to 24% of their children were also diagnosed with the condition. In cases where both parents had ADHD, the percentage of children with the disorder increased to about 33%.

This hereditary risk is also evident among siblings, with brothers and sisters of a child with ADHD facing a 26 to 42% chance of having ADHD themselves. Moreover, within families where a child has been diagnosed with ADHD, many parents also exhibit ADHD traits, which they might not recognize until their child’s diagnosis.

Understanding that there’s roughly a 25% chance of having ADHD is essential for parents, as having ADHD oneself can make parenting more challenging. Seeking advice from a doctor, discussing observations with a partner or trusted confidant, or considering a self-assessment might be helpful in such scenarios.

Genetic Testing for ADHD

Genetic testing for ADHD is primarily conducted in research settings to further our understanding. These studies aim to identify potential genetic markers, assess their significance, and explore how they may interact with environmental factors.

It is worth noting that the diagnosis of ADHD is primarily based on clinical assessment, including comprehensive evaluations of symptoms, medical history, and psychosocial factors. Genetic testing is not a routine part of diagnosing ADHD in clinical practice.

Causes of ADHD Hereditary

Numerous genetic changes have been linked to ADHD, but many of these variations remain unidentified. These variations, commonly present in global populations, do not guarantee the development of ADHD in individuals possessing them. Although most gene variations linked to ADHD have a minimal impact, individuals with ADHD usually exhibit numerous associated gene variations. These genetic differences and environmental factors contribute to an individual’s susceptibility to this intricate condition. Factors like pregnancy complications, birth-related issues, and exposure to substances like lead during development are among the environmental risk factors associated with ADHD. The interplay between genetic and environmental elements and their combined impact on ADHD development remains unclear.

In rarer cases, ADHD can stem from uncommon gene mutations or abnormalities in chromosomes. Typically, ADHD serves as one feature within a broader syndrome affecting various body systems when linked to these rare gene mutations. In individuals affected by ADHD due to rare gene mutations, a single gene mutation can be sufficient to cause the disorder.

The genes linked to ADHD are believed to play roles in brain development. Proteins generated from these genes influence diverse aspects of brain growth, including the production, growth, or organization of nerve cells (neurons). Certain genes linked to ADHD produce proteins critical for facilitating communication between neurons. These proteins contribute to the production or regulation of neurotransmitters that transmit communication signals between neurons. Additionally, some proteins are involved in the connections between neurons (synapses) where this communication occurs.

The precise mechanisms by which changes in these associated genes contribute to ADHD development remain unclear. Studies indicate that individuals with ADHD frequently exhibit reduced levels of dopamine, a neurotransmitter with multifaceted roles in cognition, motivation, behavior, and motor control. Moreover, certain brain regions may display atypical development in individuals affected by ADHD.

What Doesn’t Cause ADHD?

While ongoing discussions persist, research findings do not support the notion that ADHD is triggered by excessive sugar intake or extended television watching.

Several factors have been primarily disregarded as primary causes of ADHD, which include:

  • Parenting styles: Although effective techniques are available for parents to support a child with ADHD.
  • Dietary patterns: While a nutritious diet benefits brain health, no specific food or dietary regimen has been linked directly to causing ADHD.
  • Engagement in video games: No definitive evidence shows that playing video games causes or exacerbates ADHD. However, some children with ADHD might gravitate towards fast-paced screen games. Although these games themselves do not cause ADHD, children with ADHD might intensely focus while playing, potentially leading to prolonged gaming. Consequently, parents may consider limiting video game usage, especially for children with ADHD.

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ADHD Genetics Statistics

Statistics related to ADHD genetics reveal compelling evidence of a strong genetic component in the disorder. Family studies have consistently shown that individuals with a family history of ADHD are at a significantly higher risk of developing the disorder themselves. The heritability of ADHD, estimated to be around 70-80%, further supports the notion that genetic factors play a substantial role in its development.


8.7 Million

In 2019, the number of visits to physician offices with attention deficit disorder as the primary diagnosis was 8.7 million.

Source: NIMH

9.5%

Approximately 9.5% of American adults, ages 18 and over, will suffer from a depressive illness (major depression, bipolar disorder, or dysthymia) each year.

Source: NIMH

70-80%

The heritability of ADHD, estimated to be around 70-80%, further supports the notion that genetic factors play a substantial role in its development.

Source: NIMH


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Is ADHD Genetic or Environmental?

Experts believe that in individuals with a heightened genetic predisposition to ADHD, certain environmental factors before and after birth, as well as in childhood, could potentially trigger the manifestation of ADHD symptoms. Additionally, some environmental influences may possess enough potency to induce ADHD by directly impacting the brain. These factors might include:

Experts believe that in individuals with a heightened genetic predisposition to ADHD, certain environmental factors before and after birth, as well as in childhood, could potentially trigger the manifestation of ADHD symptoms. Additionally, some ecological influences may possess enough potency to induce ADHD by directly impacting the brain. These factors might include:

  1. Premature birth and low birth weight: Studies examining over 6,000 participants revealed that extremely premature birth or extremely low birth weight notably increased the risk for ADHD, tripling the likelihood. Further research indicated that lower birthweights and earlier premature births were associated with a heightened risk, as well.
  2. Lead exposure: An analysis encompassing more than 17,000 children from 14 studies in 2020 found that higher blood levels of lead were correlated with a fourfold increase in the risk for ADHD compared to lower blood levels. Separate research also suggested that lead exposure could potentially double the risk.
  3. Traumatic brain injury during childhood: A recent analysis conducted at the University of California Los Angeles, which involved 12,374 individuals with childhood head injuries across 24 studies, revealed that severe brain injuries in early life amplified the risk of developing ADHD later on. However, concussions and mild injuries did not demonstrate an increased risk.
  4. Fetal alcohol syndrome (FAS): Children diagnosed with FAS, a condition triggered by exposure to high levels of alcohol before birth, are approximately five times more likely to develop ADHD compared to children without FAS.

Is ADHD a Genetic Disorder?

ADHD, or Attention-Deficit/Hyperactivity Disorder, does have a genetic component, but it is not solely a genetic disorder. Genetic factors play a significant role in ADHD, and research has indicated a strong hereditary component. Studies involving twins and family histories have shown a higher likelihood of ADHD in individuals with relatives who have the condition. However, the condition is complex and influenced by a combination of genetic, environmental, and neurological factors.

While genetics contribute to ADHD susceptibility, other factors, such as environmental influences, pregnancy and birth complications, exposure to toxins like lead, premature birth, low birth weight, traumatic brain injuries, and prenatal exposure to alcohol or tobacco, can also impact the development of ADHD. Therefore, while genetic predisposition is an important factor, ADHD is best understood as a condition influenced by a combination of genetic and environmental factors.

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Is ADHD Genetic from the Mother or Father?

A parent or sibling with ADHD increases the likelihood of acquiring ADHD.
A parent or sibling with ADHD increases the likelihood of acquiring ADHD.

ADHD does not have a straightforward genetic inheritance pattern that can be attributed solely to the mother or the father. Instead, the risk of developing ADHD is influenced by a complex interplay of genetic factors from both parents, as well as environmental factors.

Research has shown that individuals with a family history of ADHD are likelier to develop the disorder. This suggests a genetic predisposition that can be inherited from both sides of the family. Having a first-degree relative (such as a parent or sibling) with ADHD increases the risk of developing ADHD compared to individuals without such a family history.

How Does ADHD Affect the Brain?

ADHD was the initial disorder identified as stemming from a shortage of a particular neurotransmitter—specifically, dopamine—and was the first disorder found to respond to drugs aimed at correcting this deficit. Individuals with ADHD, both children and adults, appear to have diminished levels of dopamine.

ADHD seems to disrupt neurotransmitter functions across four key brain regions:

Frontal cortex: This area manages high-level functions such as sustaining attention, organization, and executive function. A shortage of dopamine here could lead to inattention, organizational issues, and impaired executive function.

Limbic system: Situated deeper in the brain, this region regulates emotions. A dopamine deficit in this area might result in restlessness, inattention, or emotional fluctuations.

Basal ganglia: These neural pathways oversee brain communication. Data from all brain regions pass through the basal ganglia and then transmit to appropriate brain sites. A shortage of dopamine here might disrupt information flow, causing inattention or impulsivity.

The reticular activating system (RAS) is a primary relay network among various pathways entering and exiting the brain. A dopamine deficit in the RAS could cause inattention, impulsivity, or hyperactivity. As these regions interconnect, a deficit in one region may lead to issues in one or more of the others. ADHD arises from challenges in one or multiple of these brain regions.

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How To Find A Treatment Center that Offers Treatment for ADHD and CBT?

Finding the right therapist and centers that offer CBT for attention deficit hyperactivity disorder can take some time. Generally, you’ll get more out of CBT for ADHD therapy when you have a good relationship with your therapist. It’s always worth taking the time to find someone you can open up to comfortably. The first (or second) therapist you try may not work out, but that’s OK. They understand the importance of finding the right therapist.

Good treatment plans will include closely monitoring whether and how much the treatment helps the person’s behavior and making necessary changes. To learn more about adult CBT for ADHD recommendations and resources, contact We Level Up Florida mental health treatment center.

  • ADHD is often treated with stimulants that boost brain chemicals linked to focus and thinking. They can help with symptoms while you’re at school or work, but they can also make you less hungry or cause headaches or sleep problems.
  • Some ADHD drugs don’t involve stimulants and don’t have the same side effects. But they may not work as quickly. Your doctor might give you a combination of stimulants and non-stimulant drugs.
  • Your doctor may prescribe antidepressants to treat depression if you have comorbidity. These can take several weeks to work and may have side effects, including thoughts of suicide.
  • Antidepressants may also help with the symptoms of adult ADHD and depression, either in place of stimulants or as part of a combination of drugs to treat both conditions.

Treatment for adult ADHD usually involves a combination of medication and meetings with a therapist. ADHD medication for adults can be more effective when combined with therapies. Psychotherapy can offer ways to manage your symptoms and live a healthy life. A therapist can give you strategies to deal with everyday challenges, such as issues with friends, family, work, or school.

To find the best ADHD medication for adults, your doctor might prescribe a combination of treatments, such as medications, behavioral therapy, and talk therapy. Some antidepressant medications can also help relieve symptoms of ADHD. For instance, your doctor might prescribe imipramine, desipramine, or bupropion. They may also prescribe stimulant medications for ADHD.

In addition to prescribing medication for ADHD, a mental health professional may recommend CBT for attention deficit hyperactivity disorder (cognitive-behavior therapy) for comorbid anxiety. Some stimulant-drug treatments for ADHD may worsen anxiety symptoms in patients with comorbid anxiety disorders.

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  1. Can ADHD be genetic?

    Yes, Genetic factors contribute significantly to the risk of developing ADHD.

  2. Is ADHD hereditary or genetic?

    ADHD is hereditary and genetic. “hereditary” refers to the transmission of traits or conditions from parents to their offspring through genes. “Genetic” refers to the involvement of genes in the development and expression of a particular trait or condition.

ADHD Causes and Treatment

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Sources

[1] What is ADHD? | CDC Examining ADD vs ADHD Learn More: Is ADHD Genetic

[2] NIMH » Mental Illness (nih.gov) ADD vs ADHD Review Learn More: Is ADHD Genetic

[3] NIMH » Attention-Deficit/Hyperactivity Disorder (ADHD) (nih.gov) Learn More: Is ADHD Genetic

[4] Attention Deficit Hyperactivity Disorder – StatPearls – NCBI Bookshelf (nih.gov) ADD vs ADHD Adults Review. Learn More: Is ADHD Genetic

[5] ADHD: Reviewing the Causes and Evaluating Solutions – PMC (nih.gov) ADD vs ADHD in Adults Causes. Learn More: Is ADHD Genetic

[6] What is mental health? Evidence towards a new definition from a mixed methods multidisciplinary, international survey – PMC (nih.gov) ADD vs ADHD Symptoms Learn More: Is ADHD Genetic

[7] COMMON MENTAL HEALTH DISORDERS – Common Mental Health Disorders – NCBI Bookshelf (nih.gov) ADD vs ADHD in Female Adults Learn More: Is ADHD Genetic

[8] About Mental Health (cdc.gov) Learn More: Is ADHD Genetic

[9] Information about Mental Illness and the Brain – NIH Curriculum Supplement Series – NCBI Bookshelf Learn More: Is ADHD Genetic

[10] Effective Mood And Personality Disorder Treatment (welevelupnj.com) Learn More: Is ADHD Genetic