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How to Try CBD Depression and Anxiety Therapy?

A recent study examines CBD's possible health advantages, that's why it has gained prominence recently. According to some studies, CBD oil and other CBD products may be helpful for treating the signs and symptoms of depression. Keep reading to learn about the uses, forms, dosages, and more.

By We Level Up FL Treatment Center | Editor Yamilla Francese | Clinically Reviewed By Lauren Barry, LMFT, MCAP, QS, Director of Quality Assurance | Editorial Policy | Research Policy | Last Updated: January 20, 2023

Difference Between Anxiety and Depression – CBD Depression

Anxiety and depression difference: The fact that one term denotes a single sickness while the other denotes a collection of ailments is a significant distinction between anxiety and depression. What is the difference between anxiety and depression? The main difference between depression and anxiety is:

  • In reality, depression is one illness. There are numerous distinct symptoms (see below). And different people may experience it very differently. However, the term “depression” only refers to one illness.
  • The word “anxiety” can indicate a number of different things. We all experience anxiety occasionally, and the word “anxiety” can be used to simply describe that feeling. However, when we use the word anxiety in a medical context, it actually refers to anxiety disorder.

Some less frequent conditions are included under anxiety. These include panic disorders and phobias. However, generalized anxiety disorder is the most prevalent (GAD). In the US, a generalized anxiety disorder may affect four to five out of every 100 persons. In this post, we’ll concentrate on generalized anxiety.

What is Anxiety Disorder? CBD Depression

Periodic anxiety is a normal component of life, according to The National Institute on Mental Health. When faced with a challenge at work, before a test, or before making a crucial decision, you could experience anxiety. However, anxiety disorders involve more than just passing apprehension or terror.

Anxiety and depression difference: It’s critical to get anxiety treatment as soon as you can since, for someone with an anxiety condition, the anxiety does not go away and can actually worsen over time. The symptoms might affect daily tasks like work performance, academic progress, and interpersonal connections. Generalized anxiety disorder, panic disorder, and various phobia-related disorders are only a few of the several types of anxiety disorders.

Anxiety and depression difference: People with a generalized Anxiety disorder (GAD) display excessive Anxiety or worry, most days for at least 6 months, about many things such as personal health, work, social interactions, and everyday routine life circumstances. Fear and Anxiety can cause significant problems in areas of their life, such as social interactions, school, and work. 

What is Depression? CBD Depression

Depression (also known as Major Depressive Illness or Clinical Depression) is a common but significant mood disorder, according to the National Institute of Mental Health. It produces severe symptoms that interfere with your ability to function on a daily basis, including sleeping, eating, and working. The signs of depression must last for at least two weeks before a diagnosis may be made.

Depression treatment is required when depressive symptoms are chronic and do not go away since some types of depression are slightly different or may arise in unusual situations.

Types of Depression

  • Persistent depressive disorder (also called dysthymia): is a depressed mood that lasts for at least two years. A person diagnosed with persistent depressive disorder may have episodes of major Depression along with periods of less severe symptoms, but symptoms must last for two years to be considered a persistent depressive disorder.
  • Psychotic Depression: occurs when a person has severe depression plus some form of psychosis, such as having disturbing false fixed beliefs (delusions) or hearing or seeing upsetting things that others cannot hear or see (hallucinations). The psychotic symptoms typically have a depressive “theme,” such as delusions of guilt, poverty, or illness.
According to some studies, CBD oil for anxiety and depression and other CBD products may be helpful for treating the signs and symptoms of depression.
According to some studies, CBD oil for anxiety and depression and other CBD products may be helpful for treating the signs and symptoms of depression.

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  • Bipolar disorder: is different from Depression, but it is included in this list because someone with bipolar disorder experiences episodes of extremely low moods that meet the criteria for major Depression (called “Bipolar Depression”). But a person with bipolar disorder also experiences extreme high – euphoric or irritable – moods called “mania” or a less severe form called “hypomania.”
  • Postpartum Depression: is much more serious than the “baby blues” (relatively mild depressive and anxiety symptoms that typically clear within two weeks after delivery) that many women experience after giving birth. Women with postpartum Depression experience full-blown major Depression during pregnancy or after delivery (postpartum depression). The feelings of extreme sadness, anxiety, and exhaustion that accompany postpartum depression may make it difficult for these new mothers to complete daily care activities for themselves and/or their babies.
  • Seasonal affective disorder: is characterized by the onset of Depression during the winter months, when there is less natural sunlight. This Depression generally lifts during spring and summer. Winter Depression, typically accompanied by social withdrawal, increased sleep, and weight gain, predictably returns every year in seasonal affective disorder.

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Depression Fact Sheet

Depression Overview

Depression is a group of illnesses like depression or bipolar disorder that are connected to mood elevation or depression


Types of Depression

  • Clinical Depression: A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
  • Persistent depressive disorder: A mild but long-term form of depression.
  • Bipolar disorder: A disorder associated with episodes of mood swings ranging from depressive lows to manic highs.
  • Bipolar II disorder:  A type of bipolar disorder characterized by depressive and hypomanic episodes.
  • Postpartum depression: Depression that occurs after childbirth.

Depression Treatments

  • Support group: A place where those pursuing the same disease or objective, such as weight loss or depression, can receive counseling and exchange experiences.
  • Cognitive behavioral therapy: A conversation treatment that aimed to change the negative attitudes, actions, and feelings connected to psychiatric discomfort.
  • Counseling psychology: A subfield of psychology that handles issues with the self that are connected to work, school, family, and social life.
  • Anger management: To reduce destructive emotional outbursts, practice mindfulness, coping skills, and trigger avoidance.
  • Psychoeducation: Mental health education that also helps individuals feel supported, validated, and empowered
  • Family therapy: psychological counseling that improves family communication and conflict resolution.

Depression and Anxiety Statistics

It’s critical to understand the distinction between anxiety and depression. Anxiety, in its most basic form, is an excessive feeling of worry, whereas depression, in its most basic form, is an excessive feeling of worthlessness and hopelessness. It is conceivable for someone to experience depression and anxiety simultaneously.


6.8 million

GAD affects 6.8 million adults or 3.1% of the U.S. population, yet only 43.2% are receiving treatment.

Source: National Institute on Mental Health

19 million

19 million adults experience specific phobias, making it the most common anxiety disorder in America.  

Source: ADAA2020

17.3 million

Major depressive disorder affects approximately 17.3 million American adults or about 7.1% of the U.S. population aged 18 and older.

Source: National Institute of Mental Health


Generalized anxiety disorder and depression can both have emotional and physical symptoms.
CBD Depression: Generalized anxiety disorder and depression can both have emotional and physical symptoms.

Does CBD Help With Depression? CBD Depression

A cannabinoid is a class of natural substances that includes cannabidiol (CBD). The cannabis plant contains cannabinoids. Depending on how much of the additional cannabinoid tetrahydrocannabinol (THC) a cannabis plant contains, it may be referred to as either hemp or marijuana.

THC is related to getting “high.” However, unlike marijuana, CBD does not have any psychotropic effects. Either the hemp or marijuana plant can be used to make CBD.

A recent study examines its possible health advantages, CBD has gained prominence recently. According to some studies, CBD oil for anxiety and depression and other CBD products may be helpful for treating the signs and symptoms of depression.

CBD Depression: CBD For Depression and Anxiety

It’s crucial to realize that there hasn’t been much study done on CBD if you’re considering taking it therapeutically. There have been numerous studies over the past ten years, but the majority of them included using animals.

This means that for the time being, the potential advantages of CBD for treating human depression are essentially hypothetical.

Nevertheless, CBD does seem to have some advantages for treating depression, particularly for coping with:

  • Anxiety
  • Cognitive impairment
  • Discomfort before public speaking

THC and CBD may also be helpful for conditions potentially related to depression, such as chronic pain.

Does CBD Oil Help Bipolar Depression? CBD and Manic Depression

Energy levels, mood, and focus might change as a result of bipolar disorder, a mental health disease. Manic episodes, often known as periods of extreme energy, are common in people with bipolar disorder, and they are frequently followed by depressive episodes.

Because not every person with a mental health issue will exhibit the same pattern of behaviors or mood swings, bipolar disorder can be challenging to diagnose. Furthermore, while bipolar disorder is frequently portrayed in popular culture as a condition characterized by significant mood swings, this is not the case for all individuals who have the illness.

While prescription medications are frequently used in the traditional treatment of bipolar disorder, some people are interested in learning whether cannabidiol (CBD) might be an additional choice.

There is still a lot that experts don’t know about CBD, despite data that suggests it may have some health advantages for illnesses including anxiety and depression. This article examines if CBD can treat bipolar disorder and whether using the substance is safe for those who have a mental illness.

CBD for Postpartum Depression

In the past several years, CBD has skyrocketed in popularity as a treatment for a wide range of postpartum mood disorder symptoms, including anxiety, irritability, and insomnia. It may also be beneficial for the body’s recovery after giving birth.

Pros and Cons of CBD Oil for Anxiety & Depression (Pros and Cons of CBD Oil)

Benefits of CBD Oil for Anxiety & Depression

There are numerous ways to consume CBD oil, including pills, tinctures, sublingual drops, oral applicators, lotions, and gum. A concentrated liquid in a spray or dropper bottle is the most popular form of CBD oil. Because you don’t require a vaporizer or other specialized equipment, concentrated solutions are the simplest and most straightforward way to consume CBD oil.

Sprays and tinctures both employ droppers to administer the CBD-containing fluid under your tongue, where it is absorbed into the bloodstream. Mouth applicators and sublingual solutions both work by being absorbed through the mucosal membranes of the oral cavity. The difference is how long they remain in your system before being absorbed.

Tetrahydrocannabinol (THC), a chemical constituent of cannabis, has psychoactive effects, but cannabidiol (CBD), another chemical contained in cannabis, has therapeutic benefits and lessens some of the effects that THC causes. Numerous studies indicate that CBD oil is effective in treating a wide range of medical ailments, such as chronic pain, anxiety, depression, and acne.

Disadvantages of Using CBD Oil to Treat Anxiety & Depression

You cannot get high from CBD because it is not psychoactive. Because there are fewer negative side effects, this is also advantageous. Although they are uncommon, CBD oil side effects can include fatigue or diarrhea if the dosage is too high.

Additionally, CBD products can be quite pricey and are not widely distributed. There are still regulatory limits on the manufacturing and use of CBD oil because it is still considered a Schedule 1 substance. It is exceedingly difficult to use CBD products in some states because they are not legalized. Additionally, no CBD-infused medications have received FDA approval for use in the treatment of anxiety or depression.

Due to the fact that the FDA does not regulate some CBD products marketed in the market, these products frequently advertise erroneous medicinal claims. Numerous of these products are not quality-tested and can contain dangerous ingredients. Some may also have psychoactive effects on consumers because they contain greater than 0.3% THC.

Additionally, CBD can obstruct the body’s capacity to absorb several medications. Birth control medications, benzodiazepines, antidepressants, and anticoagulants fall within this category. The interactions between CBD oil and other psychiatric medications are not well understood.

Because both organs are necessary for the metabolism of CBD, people with liver or renal diseases are more likely to experience difficulties. There are worries that CBD oil may increase psychosis in persons with schizophrenia, while there are presently no controlled trials on how it interacts with other psychiatric medicines.

Additionally, CBD can enhance the effects of sedatives like alcohol and antidepressants. It won’t interfere with any supplements or other herbs you could be taking. Additionally, CBD may interact with several antidepressants, anti-anxiety meds, and anti-epileptic treatments.

Pros and Cons of CBD Oil for Pain

There is no way to verify that the CBD product you purchase includes what the label states because CBD is still not regulated by the FDA and is frequently not subject to any government testing regulations. (1) According to a 2017 study, 31% of CBD products purchased online contained the same amount of CBD as stated on the label. When compared to the label, the remaining 69% of the items had either too much or too little CBD.

As long as the patient is aware that more studies and solid scientific evidence are required to support CBD’s effectiveness and safety, it may be a potential non-opioid treatment alternative for musculoskeletal pain. Additionally, applying CBD oil topically appears to be a safe method of pain management. Before using any supplements, topical oils, or other alternative remedies, it is always advised to consult your doctor.

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What Does the Research Say About CBD for Anxiety and Depression? Can CBD Help Depression?

Experts think that CBD’s favorable impact on serotonin receptors in the brain accounts for some of its potential benefits for treating depression.

Depression is likely related to low serotonin levels. CBD doesn’t always increase serotonin levels, but it may change how your brain’s chemical receptors react to the serotonin that’s already there in your body.

In a 2014 study on animals, it was discovered that CBD has both antidepressant and anti-anxiety effects on these brain receptors.

A more recent 2018 analysis of prior research came to the conclusion that CBD has anti-stress properties, which may lessen depression caused by stress.

As previously mentioned, this is a field that is still actively being researched, and new studies and reviews are released every year. Information on the best ways to use the product will continue to change as researchers gain a better understanding of CBD and its potential advantages or drawbacks.

How Does CBD for Depression and Mood Compare to Antidepressant Medications?

CBD does seem to offer certain advantages over antidepressant drugs when it comes to treating depression.

The majority of antidepressants take weeks to start functioning. A 2019 animal study, however, indicated that CBD has an immediate and long-lasting antidepressant-like effect.

Additionally, CBD might have fewer negative effects than antidepressant drugs. Antidepressants frequently cause agitation, mood fluctuations, insomnia, and sexual dysfunction. CBD has not displayed the same problems.

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Will CBD Help Anxiety and Depression? CBD Depression

Anxiety and depression frequently co-occur, and those who have one are more likely to also have the other. Both seem to benefit from CBD.

According to one study, those who took 600 mg of CBD had significantly lower levels of social anxiety than those who took a placebo. In a different study, a lower dose of 300 mg was used, and anxiety levels were still decreased.

Since anxiety and low serotonin levels may be related, CBD’s impact on serotonin receptors may help to explain some of these positive effects.

CBD medicine for anxiety and depression: CBD does seem to offer certain advantages over antidepressant drugs when it comes to treating depression.
CBD medicine for anxiety and depression: CBD does seem to offer certain advantages over antidepressant drugs when it comes to treating depression.

Can CBD Oil Help With Depression? CBD Oil For Depression Side Effects

So far, CBD doesn’t appear to cause many side effects. But some people may be more sensitive to it and experience:

  • Diarrhea
  • Fatigue
  • Changes in weight or appetite

According to one study, mice exposed to levels of cannabis extracts high in CBD can develop liver damage. The mice in the study did, however, get some exceptionally high CBD doses.

Due to a dearth of studies, it is difficult to determine whether CBD has any long-term adverse effects. Experts have not yet found any significant long-term dangers.

Remember that this does not imply that there are none. Simply put, it indicates that none have been discovered as far.

The World Health Organization came to the conclusion that CBD is generally safe in a review from 2017. They stated that interactions between CBD and medicines could result in negative outcomes.

Before using CBD, be sure to discuss the possibility of adverse effects with your doctor.

How do I Use CBD for Depression? CBD and Depression

CBD for depression: Always look for reputable brands when trying to find the best CBD oil for depression or the best CBD for depression. CBD is available in four formulations:

  • Oral: This covers CBD oil for depression and anxiety, sprays, pills, and tinctures. These mixtures can be consumed on their own or added to beverages like smoothies or coffee.
  • Edible (CBD gummies for depression): Drinks and edibles, such as cbd gummies for depression and mood, are increasingly commonly accessible.
  • Vaping: One method of quickly ingesting the compounds is by vaping CBD oil. The method’s long-term safety is, however, a subject of some discussion. It may also irritate the throat and cause coughing.
  • Topical: The market for CBD-infused creams, lotions, and beauty products is booming right now. These goods contain CBD that you can directly apply to your skin. In contrast to uses for mental health, this formulation is probably best for treating pain.

CBD Dosage For Depression

CBD for depression: There is no universal agreement on the dosages that should be used for different illnesses, and research studies use a variety of dosages. It’s also crucial to remember that there is no standard dosage for CBD if you do decide to give it a try. The dosage that is appropriate for your needs may change as a result of research suggesting that individuals may react differently to different dosages.

Some dosages that have been used in research studies for different conditions include:

  • Depression and Anxiety: 300 to 600 mg
  • Bowel disease: 10 mg per day
  • Cancer-related pain: 50 to 600 mg per day
  • Parkinson’s disease: 75 to 300 mg per day

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The exact definition of dual diagnosis (also referred to as co-occurring disorders) can differ between institutions.  However, it is generally described as the specific treatment of someone who has been diagnosed with a substance use disorder and a mental health disorder at the same time.

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CBD FOR Depression FAQs

  1. Is CBD a depressant or stimulant? CBD Stimulant or Depressant?

    Is CBD a stimulant or depressant? Is CBD depressant or stimulant? As a central nervous system depressant, CBD has the potential to make you sleepy. However, it is not recommended as a sleep aid due to its long half-life of 50–60 hours in the body. Half-life is the amount of time that passes before the drug is completely gone after a dose.

  2. Can CBD Cause Depression? Can Cbd Make Depression Worse?

    Can CBD oil make depression worse? There isn’t any concrete proof of CBD causes depression. But it’s crucial to be aware of that possible side effect because weariness is linked to depression. If you want to use CBD to treat your depression, think about how it might affect the prescription drugs you already take.

  3. What is the Best CBD Strain For Anxiety and Depression?

    CBD cannabis strains to ease anxiety are Remedy, ACDC, Lifter, Charlotte’s Web, Cherry Wine, Ringo’s Gift, Harle-Tsu, and Sour Tsunami.

  4. Can CBD Help With Seasonal Depression?

    Selecting strains and goods with high CBD content is advised to treat seasonal depression.

  5. How Long Does It Take Cbd Oil To Help Depression?

    CBD oils or capsules may be most helpful if you need to relieve stress, anxiety, depression, or sleep-related issues. Within 30 minutes, the results ought to become apparent. If you want to get rid of bodily pain, try using a balm or lotion.

  6. Best CBD Ratio For Depression

    The best CBD: THC ratio for depression and anxiety is 1:1, with one or more parts CBD to each part THC.

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