Does CBD Help With Depression? Does It Work? Effectiveness & Uses

Does CBD help with depression? A recent study examines CBD’s possible health advantages, that’s why it has gained prominence recently. According to some studies, CBD oil and other CBD products may be helpful for treating the signs and symptoms of depression. Keep reading to learn about the uses, forms, dosages, and more.

Does CBD Help With Depression?

CBD, a natural compound, has become popular due to research suggesting potential health benefits, including the treatment of depression. Some early studies on CBD and depression show promising results.

CBD is distinct from tetrahydrocannabinol (THC) as it doesn’t cause euphoria or a “high.” Unlike THC, CBD doesn’t produce these effects on the body. This article explores the potential of CBD to alleviate depression symptoms. However, CBD may not be suitable for everyone, and there are other factors to consider before using it as a treatment for any condition.

What is CBD for Depression and Anxiety?

Cannabidiol (CBD) is a compound found in the Cannabis sativa plant, distinct from THC. In the U.S., it’s legally produced from hemp and available in various forms, such as oils, capsules, and sprays for oral use or lotions for skin application. CBD is also added to food, drinks, pet products, cosmetics, and even infused into fabric. It can be purchased online, in specialty stores, or a local grocery or drugstore, depending on state laws.

Scientists are researching CBD as a potential treatment for diseases like Parkinson’s and multiple sclerosis, as well as mental health conditions such as schizophrenia, PTSD, anxiety, and depression.

While there’s some evidence suggesting CBD may help with anxiety and depression, there’s limited research, and caution is advised.

What Evidence Supports the Use of CBD for Anxiety and Depression?

The research exploring the use of CBD depression treatment has shown promising findings. Some studies suggest that CBD may have a positive impact on alleviating symptoms associated with these mental health conditions. However, more comprehensive research is needed to establish the full extent of CBD’s effectiveness and its optimal dosage for treating anxiety and depression.

Individuals considering CBD as part of their mental health regimen should consult with a healthcare professional for personalized advice and guidance based on their specific circumstances.

Doctors are uncertain about the exact way CBD improves anxiety and depression symptoms. CBD influences over 65 brain receptors, including some that impact serotonin levels—a mood-controlling brain chemical. While existing anxiety and depression medications enhance serotonin levels, CBD may affect other receptors and brain pathways, contributing to its potential benefits.

Is it Safe to Use CBD Oil For Depression?

Using CBD oil for depression is generally safe, but it’s crucial to be cautious and seek guidance from a healthcare professional. Although research indicates potential therapeutic benefits for managing depression symptoms with CBD, individual reactions may differ. Consider factors like the quality of the CBD product, proper dosing, and possible interactions with other medications.

Before adding CBD oil to your depression treatment, contact We Level Up FL mental health center for personalized advice. Mental health professionals can assess your situation, address concerns about potential side effects, and reassess if CBD aligns with your overall mental health plan.

Before trying CBD for anxiety or depression, consider these factors:

  • The CBD amount in the product may differ from what the label indicates.
  • The CBD product could contain undisclosed ingredients, including THC, the intoxicating component of marijuana.
  • Lack of government oversight may lead to product contamination during manufacturing.
  • The effectiveness of CBD consumption through ingestion, inhalation, or skin application is not well understood by doctors.
  • While studies have explored CBD at different doses, the optimal amount, frequency, and duration for effectiveness remain unknown.
  • The FDA is collaborating with lawmakers to establish a system for evaluating and approving CBD products.

We need more research to understand how safe CBD is. While it’s generally well-tolerated and severe side effects are rare, we need to learn more about its long-term effects, the right amount to use, and how it might interact with other medications. Most studies have only looked at short-term use, and we need more big studies to be sure how safe it is to use CBD for a long time.

Another thing to consider is that the quality of CBD products can vary a lot. There are no rules for making CBD, and products can be different. This makes it hard to know how safe each product is. To make sure CBD is used safely, we need more research, especially studies that look at its safety over a long time, and rules to make sure all CBD products are made the same way.

Get depression counseling that works. Discover professional help from We Level Up Florida’s mental health therapists. Start getting support with a free call to our mental health hotline.

We Level Up FL Mental Health Center Tips For Taking CBD and Depression

✅ When using CBD for depression, start with a low dose and gradually increase if needed, as individual responses vary.

✅ Choose high-quality products from reputable sources to ensure accuracy in dosage and avoid potential contaminants.

✅ Consult with a healthcare professional before incorporating CBD into your depression management plan for personalized guidance.

Get Help. Get Better. Get Your Life Back.

Searching for Accredited Dual Diagnosis Mental Health Centers Near You?

Even if therapy failed previously, or are in the middle of a difficult crisis, we stand ready to support you. Our trusted behavioral health specialists will not give up on you. When you feel ready or just want someone to speak to about counseling alternatives to change your life call us. Even if we cannot assist you, we will lead you to wherever you can get support. There is no obligation. Call our hotline today.

FREE 24/7 Dual Diagnosis Mental Health Services Hotline

How Does CBD for Depression Compare to Antidepressant Medications?

Choosing between CBD and traditional antidepressant medications involves understanding how they affect the brain’s neurotransmitter systems. Antidepressants like SSRIs increase serotonin availability, positively impacting mood by slowing its reuptake in the brain. CBD’s impact on depression isn’t apparent, but it may influence serotonin receptors and the endocannabinoid system, regulating mood and stress response.

Both CBD and antidepressants aim to adjust neurotransmitter systems, but they may target different pathways and receptors. Individual responses vary, and while antidepressants undergo rigorous testing and have established protocols, CBD’s regulation is evolving, leading to variations in quality.

Consult We Level Up FL to decide based on individual health, preferences, and scientific evidence. Approach CBD for depression as a complementary or alternative option under professional guidance, given the ongoing research in this field.

Does CBD help with depression? It's crucial to consult with a healthcare professional before using CBD for depression to understand potential side effects and ensure its compatibility with your overall health and any existing medications.

What are the Possible Side Effects of CBD for Depression?

CBD has the potential to interact with specific medications, altering their effects on your body and potentially causing harmful side effects. These medications may include certain antibiotics, antidepressants, cholesterol medications, and blood thinners.

Possible side effects of CBD for depression may also include the following:

  • Dry Mouth: CBD may reduce saliva production, leading to dry mouth.
  • Fatigue: Some individuals may experience tiredness or drowsiness.
  • Changes in Appetite: CBD may influence appetite, leading to increased or decreased hunger.
  • Diarrhea: In some cases, CBD use has been associated with gastrointestinal issues like diarrhea.
  • Interactions with Medications: CBD can interact with certain medications, affecting their efficacy.
  • Nausea: While uncommon, some individuals may experience nausea as a side effect of CBD.

To minimize the risk of side effects from using CBD for depression, consider the following precautions:

  • Consult with a Healthcare Professional: Before incorporating CBD into your depression management plan, consult with a doctor or mental health professional. They can provide personalized advice based on your health history and existing medications.
  • Start with a Low Dose: Begin with a low CBD dosage and gradually increase if needed. Starting low allows you to assess your body’s response and helps avoid potential adverse effects.
  • Choose High-Quality Products: Select reputable CBD products from trusted sources. Look for third-party testing and precise labeling to ensure the product’s quality and authenticity.
  • Be Mindful of Interactions: Be aware of potential interactions between CBD and other medications you may be taking. Discuss any concerns with your healthcare provider to prevent adverse reactions.
  • Monitor Your Body’s Response: Pay attention to how your body responds to CBD. If you experience any discomfort or unexpected reactions, consult with your healthcare provider promptly.
  • Consider Form and Delivery Method: Different forms of CBD (oils, capsules, gummies) and delivery methods (ingestion, inhalation, topical) may have varying effects. Experiment cautiously and find what works best for you.
  • Maintain Open Communication: Keep an open line of communication with your healthcare provider throughout your CBD usage. Regular check-ins allow for adjustments, ensuring your treatment plan aligns with your mental health needs.

It’s crucial to consult with a healthcare professional before using CBD for depression to understand potential side effects and ensure its compatibility with your overall health and any existing medications.

Ryan Zofay forming a circle and hugging friends.

End the Emotional Pain. Get Your Life Back.

Feeling Depressed, Anxious or Struggling with Mental Health Illness? Get Safe Comfortable Mental Health Dual Diagnosis High-Quality Therapy From Counselors That Care. Begin Your Recovery Now.

Hotline (855) 940-6125

Is It Worth Considering CBD for Managing Depression?

Deciding if CBD is suitable for managing depression involves considering individual factors. Although some CBD and depression studies suggest potential benefits, research is ongoing, and people’s responses to CBD can differ. Consulting with a healthcare professional before adding CBD to your depression plan is crucial for the following:

  • Personalized guidance.
  • Assessing interactions with medications
  • Navigating CBD complexities for your mental health.

It’s also essential to understand the quality of CBD products, with reliable sources and clear labeling contributing to a safer and more practical experience. Ultimately, the decision to try CBD for depression should be a collaborative one with healthcare professionals considering your specific needs and mental health strategy.

How to Use CBD for Depression?

Using CBD for depression requires careful consideration and consultation with a healthcare professional. Here is comprehensive guidance on how to incorporate CBD into your depression management plan:

  • Please Consult with a Healthcare Professional: Before starting any CBD regimen, discuss it with your healthcare provider. They can assess your overall health potential interactions with medications and provide personalized advice.
  • Choose High-Quality Products: Select reputable CBD products from trusted sources. Look for third-party testing and precise labeling to ensure the product’s quality and authenticity.
  • Start with a Low Dose: Begin with a low CBD dosage and monitor your response. Gradually increase the dose if needed, based on how your body reacts.
  • Consider the Form of CBD: CBD is available in various forms, including oils, capsules, gummies, and topical products. Choose a treatment approach that aligns with your preferences and lifestyle.
  • Be Consistent: Consistency is critical. Incorporate CBD into your routine consistently, following the recommended dosage and schedule provided by your healthcare professional.
  • Monitor and Adjust: Consider how CBD affects your mood and overall well-being. If needed, work with your healthcare provider to adjust the dosage or form of CBD.
  • Combine with Other Strategies: CBD can complement other depression management strategies. It’s essential to continue proven approaches such as therapy, medication, and lifestyle changes as recommended by your healthcare provider.
  • Be Patient: Results may take time. Give CBD time to take effect, and communicate regularly with your healthcare provider about your experiences and any changes in symptoms.

Remember, individual responses to CBD can vary, and its effectiveness is still an area of ongoing research. Always prioritize open communication with your healthcare provider for the most personalized and practical approach to using CBD for depression.

Caution in Using CBD For Depression

Caution in using CBD for depression stems from several factors, and understanding the scientific rationale is crucial.

  • Limited Research: While preliminary studies indicate the potential benefits of CBD for depression, the body of scientific evidence is still evolving. Rigorous, large-scale clinical trials are needed to establish its efficacy, optimal dosage, and long-term effects.
  • Variability in Products: CBD products vary widely in quality, purity, and concentration. The lack of standardized regulations can result in inconsistent formulations, potentially affecting the reliability and effectiveness of CBD for depression.
  • Interactions with Medications: CBD can interact with certain medications, impacting their metabolism and efficacy. Caution is necessary, especially for individuals taking other medications for depression or related conditions, as the potential for adverse interactions exists.
  • Individual Variability: Responses to CBD are highly individualized. Factors such as genetics, overall health, and the specific form of CBD used can influence how it affects individuals. What works for one person may have a different effect on another.
  • Potential Side Effects: While generally well-tolerated, CBD may cause side effects such as dry mouth, fatigue, or changes in appetite. Understanding and monitoring these possible side effects is crucial for individuals considering CBD for depression.

In summary, using CBD for depression is grounded in need for more robust scientific evidence, the variability in product quality, the potential for interactions with medications, individual variability in response, and the awareness of potential side effects. Seeking guidance from a healthcare professional ensures a more informed and safe approach to incorporating CBD into depression management.

First-class Facilities & Amenities

World-class High-Quality Mental Health Services & Behavioral Health Substance Abuse Treatment

Rehab Centers Tour

Renowned Mental Health Centers. Serene Private Facilities. Inpatient Rehab Programs Vary.

Mental Health Helpline (855) 940-6125

Proven recovery success experience, backed by a Team w/ History of:


Years of Unified Experience


5-Star Reviews Across Our Centers


Recovery Successes

  • Comprehensive Dual-Diagnosis Treatment
  • Complimentary Family & Alumni Programs
  • Coaching, Recovery & Development Events
  • Comfortable Onsite Medical Detox Center

A word from We Level Up FL for the use of CBD for depression

The current status regarding CBD’s potential as a depression treatment underscores the necessity for additional research. Evidence supporting CBD’s antidepressant effects predominantly originates from animal studies or small-scale trials. One of the most extensive reviews of this research has concluded that the available evidence does not provide sufficient strength to recommend CBD as a standalone treatment for depression.

For individuals experiencing symptoms of depression, seeking consultation with a doctor or mental health professional is imperative. Depression, if untreated, can escalate over time, but effective treatments, including psychotherapy and medications, are available. Suppose there’s an interest in incorporating CBD alongside other therapies. In that case, it is crucial to discuss with a healthcare provider first to ensure a comprehensive understanding of usage and potential interactions with medications.

Suppose you or someone you know is dealing with depression. In that case, We Level Up Florida Mental Health Treatment Center provides personalized care with a team of experienced professionals. Begin your journey towards better health by taking the first step towards healing. Get help. Call We Level Up FL now. Each call is free and confidential.

World-class, Accredited, 5-Star Reviewed, Effective Mental Health Dual Diagnosis Programs. Complete Integrated Inpatient Rehab with Free Post Discharge Therapy Planning.

CALL (855) 940-6125

End the Emotional Pain Rollercoaster. Gain Stability & Happiness Through Recovery Treatment. Start Mental Health Counseling Today. Get Free No-obligation Guidance by Behaviroal Health Specialists Who Understand Mental Health Recovery.

Clinical Depression Informative Video

Experience Transformative Recovery at the We Level Up Treatment Center.

See our authentic success stories. Get inspired. Get the help you deserve.

We Level Up Treatment Centers for Drug Alcohol Rehab Detox Behavioral Mental Health Dual Diagnosis Therapy We Level Up Treatment Centers for Drug Alcohol Rehab Detox Behavioral Mental Health Dual Diagnosis Therapy We Level Up Treatment Centers for Drug Alcohol Rehab Detox Behavioral Mental Health Dual Diagnosis Therapy
Hotline (855) 940-6125
Voluntarily testimonials from the We Level Up Treatment Center network vary. Not intended as a guaranteed treatment or outcome as each person's journey is unique.

Start a New Life

Begin with a free call to a behavioral health treatment advisor. Learn more about our dual-diagnosis programs. The We Level Up treatment center network delivers recovery programs that vary by each treatment facility. Call to learn more.

  • Personalized Care
  • Caring Accountable Staff
  • World-class Amenities
  • Licensed & Accredited
  • Renowned w/ 5-Star Reviews

We’ll Call You

Search We Level Up FL Does CBD Help With Depression? Mental Health Topics & Resources

[1] Wieckiewicz G, Stokłosa I, Stokłosa M, Gorczyca P, Pudlo R. Cannabidiol (CBD) in the Self-Treatment of Depression-Exploratory Study and a New Phenomenon of Concern for Psychiatrists. Front Psychiatry. 2022 Mar 22;13:837946. Doi: 10.3389/fpsyt.2022.837946. PMID: 35392393; PMCID: PMC8980587.

[2] Oberbarnscheidt T, Miller NS. The Impact of Cannabidiol on Psychiatric and Medical Conditions. J Clin Med Res. 2020 Jul;12(7):393-403. Doi: 10.14740/jocmr4159. Epub 2020 Jun 25. PMID: 32655732; PMCID: PMC7331870.

[3] Mental Health Conditions: Depression and Anxiety – Centers for Disease Control and Prevention (CDC)

[4] Chand SP, Arif H. Depression. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:

[5] Beevers CG. Editorial overview: The assessment, etiology, and treatment of unipolar depression. Curr Opin Psychol. 2015 Aug 1;4:v-viii. Doi: 10.1016/j.copsyc.2015.05.003. PMID: 26273694; PMCID: PMC4528375.

[6] What is Depression? – Substance Abuse and Mental Health Services Administration (SAMHSA)

[7] Depression Medicines – Food and Drug Administration (FDA)

[8] Depression: MedlinePlus Medical Encyclopedia

[9] Major depressive disorder: Validated treatments and future challenges – National Institutes of Health (NIH)

[10] Depression Treatment For Veterans – Veterans Affairs (.gov)